On clean, dry skin, apply a pea-size amount to each facial area (forehead, chin, nose, each cheek) once daily. Spread a thin layer; avoid eyes, eyelids, lips, and inside the nose/mouth. Wash hands after. If directed for a non-facial area, follow your prescriber’s exact instructions.

Usually mild and temporary: dryness, burning/stinging, itching, redness, or irritation at the application site. Stop and contact your clinician if you develop severe irritation, swelling, hives, blistering, or signs of an allergic reaction.

Many patients notice calmer skin in 2–4 weeks, with clearer results by 8–12 weeks when used daily. Keep using as directed unless your clinician tells you to stop.

Yes—use a gentle cleanser, non-comedogenic moisturizer, and broad-spectrum sunscreen. If you also use actives (retinoids, AHAs/BHAs, benzoyl peroxide), introduce slowly or alternate days to minimize irritation. Apply makeup after the cream has fully absorbed.

Do not use on broken skin or if you’ve had a previous allergy to ivermectin or formulation ingredients. Pregnant or breastfeeding patients should use only if a clinician determines it’s appropriate.